abstract：PURPOSE:Akathisia remains a common side effect especially from antipsychotic medication. If the condition is diagnosed the management options are limited. SUBJECTS/METHODOLOGY: We tested a structured relaxation program on nine patients with a diagnosis of schizophrenia suffering from akathisia. All patients were rated ...

journal_title：Neuropsychiatric disease and treatment

authors： Hansen LK,L'allemand T,Thiry F,Baldwin DS

更新日期：2010-05-25 00:00:00

abstract：:The aim of this study was to explore the impact of mental illness among patients with migraine. We performed MedLine and PsycINFO searches from 1980 to 2008. Research has systematically documented a strong bidirectional association between migraine and psychiatric disorders. The relationship between migraine and psych...

journal_title：Neuropsychiatric disease and treatment

authors： Pompili M,Serafini G,Di Cosimo D,Dominici G,Innamorati M,Lester D,Forte A,Girardi N,De Filippis S,Tatarelli R,Martelletti P

更新日期：2010-04-07 00:00:00

abstract：:About half of all bipolar patients have an alcohol abuse problem at some point of their lifetime. However, only one randomized, controlled trial of pharmacotherapy (valproate) in this patient population was published as of 2006. Therefore, we reviewed clinical trials in this indication of the last four years (using mo...

journal_title：Neuropsychiatric disease and treatment

authors： Azorin JM,Bowden CL,Garay RP,Perugi G,Vieta E,Young AH

更新日期：2010-03-24 00:00:00

abstract：PURPOSE:Abnormalities in both cortisol and dehydroepiandrosterone (DHEA) have been reported in psychiatric disorders. Analysis of saliva, urine and blood cortisol and DHEA levels provides an index of hormone levels over a short time period. Unlike such conventional measures, fingernails incorporate endogenous hormones ...

journal_title：Neuropsychiatric disease and treatment

authors： Warnock F,McElwee K,Seo RJ,McIsaac S,Seim D,Ramirez-Aponte T,Macritchie KA,Young AH

更新日期：2010-02-03 00:00:00

abstract：:At the time of this study, there were five known patients with Wilson disease (WD) in Iceland. The mutation, a 7-bp deletion in exon 7 on chromosome 13 for WD, is only known in Iceland. In twenty healthy Icelandic heterozygotes for WD and their age- and gender-matched controls, copper concentration in plasma, cerulopl...

journal_title：Neuropsychiatric disease and treatment

authors： Tórsdóttir G,Gudmundsson G,Kristinsson J,Snaedal J,Jóhannesson T

更新日期：2009-01-01 00:00:00

abstract：:Melatonin (n-acetyl-5-methoxy-tryptamine), a naturally occurring indole produced mainly by the pineal gland, is a well known antioxidant. Stroke (cerebral ischemia) is the second leading cause of death worldwide. To date, however, effective and safe treatment for stroke remains unavailable. Melatonin is both lipid- an...

journal_title：Neuropsychiatric disease and treatment

authors： Lin HW,Lee EJ

更新日期：2009-01-01 00:00:00

abstract：:Co-morbid depression is common in patients with diabetes mellitus and has a negative impact on diabetes self-care, adherence to treatment and the development of complications. Effective treatment of depression has been associated with improvement in metabolic parameters. We evaluated the feasibility of a two question ...

journal_title：Neuropsychiatric disease and treatment

authors： Abrahamian H,Hofmann P,Prager R,Toplak H

更新日期：2009-01-01 00:00:00

abstract：:The pharmacodynamic properties of fluvoxamine maleate include the modulation of different populations of serotonergic, dopaminergic, and sigma receptors and/or transporters, a complex pattern of activity that may account for its efficacy in the treatment of obsessive-compulsive disorder (OCD). Nevertheless, its pharma...

journal_title：Neuropsychiatric disease and treatment

authors： Ordacgi L,Mendlowicz MV,Fontenelle LF

更新日期：2009-01-01 00:00:00

abstract：:Pregabalin is a new antiepileptic medication that works by binding to alpha 2 delta subunit of the voltage-dependent calcium channels present in presynaptic neurons. Its pharmacokinetic advantages include rapid and almost complete absorption, lack of protein binding, linear kinetics, absence of enzyme induction, and a...

journal_title：Neuropsychiatric disease and treatment

authors： Arain AM

更新日期：2009-01-01 00:00:00

abstract：:This study evaluates the correlation between failure to develop spontaneous imitation and language skills in pervasive developmental disorders. Sixty-four children between the age of 3 and 8 years were assessed using the Autism Diagnostic Interview-Revised (ADI-R), the Childhood Autism Rating Scale (CARS), and the Aut...

journal_title：Neuropsychiatric disease and treatment

authors： De Giacomo A,Portoghese C,Martinelli D,Fanizza I,L'abate L,Margari L

更新日期：2009-01-01 00:00:00

abstract：:Alzheimer's disease is the most common cause of dementia in older adults. The clinical features include progressive memory decline as well as cognitive deficits with executive dysfunction, language, visual perceptual difficulties, apraxia and agnosia. During the moderate to severe stage of the disease, there is a majo...

journal_title：Neuropsychiatric disease and treatment

authors： Puangthong U,Hsiung GY

更新日期：2009-01-01 00:00:00

abstract：:Despite its high prevalence and individual as well as societal burden, migraine remains underdiagnosed and undertreated. In recent years, the options for the management of migraine patients have greatly expanded. A number of drugs belonging to various pharmacological classes and deliverable by several routes are now a...

journal_title：Neuropsychiatric disease and treatment

authors： Fumal A,Schoenen J

更新日期：2008-12-01 00:00:00

abstract：:Mycophenolate mofetil (MMF) has been used to treat myasthenia gravis (MG) for over 10 years. MMF's use in the MG population stems from its theoretical mechanism of action and the medical literature that supports its benefit in MG patients. Recently, two large, double-blinded, placebo-controlled, randomized clinical tr...

journal_title：Neuropsychiatric disease and treatment

authors： Heatwole C,Ciafaloni E

更新日期：2008-12-01 00:00:00

abstract：:Traumatic brain injury (TBI) is widespread and leads to death and disability in millions of individuals around the world each year. Overall incidence and prevalence of TBI are likely to increase in absolute terms in the future. Tackling the problem of treating TBI successfully will require improvements in the understa...

journal_title：Neuropsychiatric disease and treatment

authors： Flanagan SR,Cantor JB,Ashman TA

更新日期：2008-10-01 00:00:00

abstract：:Previous studies on cognitive training in Alzheimer's disease (AD) were principally aimed at making patients learn items not related to functional needs. However, AD patients also experience difficulties with instrumental activities of daily living (IADL). The goal of the present multiple baseline case report study wa...

journal_title：Neuropsychiatric disease and treatment

authors： Thivierge S,Simard M,Jean L,Grandmaison E

更新日期：2008-10-01 00:00:00

abstract：:Recent findings in animal models of paraplegia suggest that specific nonbenzodiazepine anxiolytics may temporarily restore locomotor functions after spinal cord injury (SCI). Experiments using in vitro models have revealed, indeed, that selective serotonin receptor (5-HTR) ligands such as 5-HTR(1A) agonists, known as ...

journal_title：Neuropsychiatric disease and treatment

authors： Guertin PA

更新日期：2008-08-01 00:00:00

abstract：:Headaches in children and adolescents are still under-diagnosed. 75% of children are affected by primary headache by the age of 15 with 28% fitting the ICHD2 criteria of migraine. Migraine is considered a chronic disorder that can severely impact a child's daily activities, including schooling and socializing. Early r...

journal_title：Neuropsychiatric disease and treatment

authors： Kabbouche MA,Gilman DK

更新日期：2008-06-01 00:00:00

abstract：:Delirium occurs in 23% of sepsis patients, in which pro-inflammatory cytokines and nitric oxide are suggested to be involved. However, in animal experiments, even a subseptic dose of lipopolysaccharide (LPS) injection induces both pro-inflammatory cytokines and inducible nitric oxide synthase in the brain, suggesting ...

journal_title：Neuropsychiatric disease and treatment

authors： Maeda S,Nakatsuka I,Hayashi Y,Higuchi H,Shimada M,Miyawaki T

更新日期：2008-06-01 00:00:00

abstract：:Pramipexole is a non-ergot dopamine agonist shown to be efficacious in the treatment of Parkinson's disease (PD). This review addresses the literature concerning pramipexole's efficacy in treating motor and non-motor symptoms in PD, its impact on the development of dyskinesias and response fluctuations, the issue of n...

journal_title：Neuropsychiatric disease and treatment

authors： Constantinescu R

更新日期：2008-04-01 00:00:00

abstract：:Few data are available on the applicability of both the criteria proposed by Silberstein and Lipton (S-L) and the International Classification of Headache Disorders-II (ICHD-II) in the classification of children and adolescents with chronic daily headache (CDH). The International Headache Society recently added revise...

journal_title：Neuropsychiatric disease and treatment

authors： Cuvellier JC,Couttenier F,Auvin S,Vallée L

更新日期：2008-02-01 00:00:00

abstract：:An 87-year-old woman had both Lewy body dementia and normal pressure hydrocephalus simultaneously. One should not automatically exclude the possibility of normal pressure hydrocephalus simply because another neurodegenerative disorder is present, especially if the second disorder masks typical symptoms of normal press...

journal_title：Neuropsychiatric disease and treatment

authors： Alisky J

更新日期：2008-02-01 00:00:00

abstract：:Panic disorder (PD) is a disabling condition which appears in late adolescence or early adulthood and affects more frequently women than men. PD is frequently characterized by recurrences and sometimes by a chronic course and, therefore, most patients require long-term treatments to achieve remission, to prevent relap...

journal_title：Neuropsychiatric disease and treatment

authors： Marchesi C

更新日期：2008-02-01 00:00:00

abstract：:Stem cells are self-renewing undifferentiated cells that give rise to multiple types of specialized cells of the body. In the adult, stem cells are multipotents and contribute to homeostasis of the tissues and regeneration after injury. Until recently, it was believed that the adult brain was devoid of stem cells, hen...

journal_title：Neuropsychiatric disease and treatment

authors： Taupin P

更新日期：2007-12-01 00:00:00

abstract：:The essential features of bipolar affective disorder involve the cyclical occurrence of high (manic or hypomanic episodes) and low mood states. Depressive episodes in both bipolar I and II disorder are more numerous and last for longer duration than either manic or hypomanic episodes. In addition depressive episodes a...

journal_title：Neuropsychiatric disease and treatment

authors： Gajwani P,Muzina DJ,Kemp DE,Gao K,Calabrese JR

更新日期：2007-12-01 00:00:00

abstract：AIMS:To estimate differences in the incidence of recorded traumatic head injuries by gender, age, severity, and geographical area. METHODS:The study was prospective and nationwide. Data were collected from all hospitals, emergency units and healthcare centers in Iceland regarding all Icelandic children and adolescents...

journal_title：Neuropsychiatric disease and treatment

authors： Halldorsson JG,Flekkoy KM,Gudmundsson KR,Arnkelsson GB,Arnarson EO

更新日期：2007-12-01 00:00:00

abstract：:Epilepsy is a common pediatric neurologic disorder that is difficult to manage in a substantial portion of children. Levetiracetam (LEV) is a novel antiepileptic drug (AED) that has recently been approved as add-on treatment for various seizure types in epilepsy populations that include children: for refractory partia...

journal_title：Neuropsychiatric disease and treatment

authors： Wheless JW

更新日期：2007-08-01 00:00:00

abstract：:Compliance and relapse are major issues in the treatment of psychotic disorders. About 50% of subjects with schizophrenia do not comply with treatment and relapse rates of 65% are reported after one year and 80% after two years. Drug treatments are effective against psychotic symptoms, but cannot promote functional re...

journal_title：Neuropsychiatric disease and treatment

authors： Saba G,Mékaoui L,Leboyer M,Schürhoff F

更新日期：2007-08-01 00:00:00

abstract：:Prior studies have demonstrated the importance of treatment persistence with anti-psychotic agents in sustaining control of schizophrenic symptoms. However, the conventional approach in measuring treatment persistence tended to use only the first prescription episode even though some patients received multiple prescri...

journal_title：Neuropsychiatric disease and treatment

authors： Ren XS,Qian S,Kazis LE

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Anterior cingulate cortex (ACC) dysfunction is implicated in schizophrenia by numerous strands of scientific investigation. Functional neuroimaging studies of the ACC in schizophrenia have shown task-related hypo-activation, hyper-activation, and normal activation relative to comparison subjects. Interpretin...

journal_title：Neuropsychiatric disease and treatment

authors： Adams R,David AS

更新日期：2007-02-01 00:00:00

abstract：:Family history, which includes both common environmental and genetic effects, is associated with an increased risk for many neuropsychiatric diseases. Investigators have identified several disease-causing mutations for specific neuropsychiatric disorders that display Mendelian segregation. Such discoveries can lead to...

journal_title：Neuropsychiatric disease and treatment

authors： Keller MA,Gwinn K,Nash J,Horsford J,Zhang R,Rich SS,Corriveau RA

更新日期：2007-01-01 00:00:00

abstract：:Obsessive compulsive and impulsive symptoms are prevalent in patients with Tourette's Syndrome (TS) and well recognized as part of the TS spectrum. However, some complex obsessive compulsive and impulsive behaviors may be mistaken for other symptoms, such as complex tics or psychotic behavior. In addition, the overlap...

journal_title：Neuropsychiatric disease and treatment

authors： Palumbo D,Kurlan R

更新日期：2007-01-01 00:00:00

abstract：:Dopaminergic agents, anticonvulsants, benzodiazepines, opiates, and iron supplementation comprise the classes of medications commonly used to treat restless legs syndrome (RLS), which is a disorder that is estimated to affect about 1 in 10 individuals worldwide and impacts an affected patient's sleep, mood, daytime fu...

journal_title：Neuropsychiatric disease and treatment

authors： Kushida CA

更新日期：2006-12-01 00:00:00

abstract：:Neuropsychiatric symptoms are common in older adults with dementia and can be associated with a rapid decline in cognitive and functional status. This article reviews the current literature supporting the use of atypical antipsychotic medications in this population. Among the currently available atypical antipsychotic...

journal_title：Neuropsychiatric disease and treatment

authors： Lee PE,Gill SS,Rochon P

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To study clinical correlates of religiosity in Parkinson's disease (PD). METHODS:Measures of life goals, religiosity, mood, and neuropsychologic function were assessed in 22 persons with mid-stage PD and 20 age-matched healthy controls. Levodopa dose equivalents (LDE) were also computed for the patients. RE...

journal_title：Neuropsychiatric disease and treatment

authors： McNamara P,Durso R,Brown A

更新日期：2006-09-01 00:00:00

abstract：:Restless legs syndrome (RLS) is one of the commonest movement disorders affecting sleep and also daytime functioning. The prevalence may be 8%-10% of the white Caucasian population. The diagnosis is simple and is based on a well-validated clinical questionnaire, yet misdiagnosis is common and the condition remains und...

journal_title：Neuropsychiatric disease and treatment

authors： Byrne R,Sinha S,Chaudhuri KR

更新日期：2006-06-01 00:00:00

abstract：:A series of cases are reported in which patients on aripiprazole have developed akathisia, although the literature states that the rate is negligible. ...

journal_title：Neuropsychiatric disease and treatment

authors： Basu R,Brar JS

更新日期：2006-06-01 00:00:00

abstract：INTRODUCTION:Essential tremor (ET) is the most common movement disorder in the adult population. At present ET treatment shows limited efficacy, particularly in patients with severe and disabling symptoms. This study evaluates the clinical efficacy of mirtazapine in an untreated ET patient population. MATERIALS AND ME...

journal_title：Neuropsychiatric disease and treatment

authors： Uccellini D,Grampa G,La Spina I,Nasuelli D,Neromante I,Politini L,Reverberi F,Porazzi D,Carli V,Camardese G

更新日期：2006-03-01 00:00:00

abstract：:Fluvoxamine is a selective-serotonin reuptake inhibitor (SSRI) that has proved effective in large double-blind, randomized, controlled trials involving patients with social anxiety disorder (SAD), obsessive-compulsive disorder (OCD), and panic disorder. Improvements have also been demonstrated in patients with post-tr...

journal_title：Neuropsychiatric disease and treatment

authors： Irons J

更新日期：2005-12-01 00:00:00

abstract：:Conversion disorder has a history that may reach back into antiquity, and it continues to present a clinical challenge to both psychiatrists and neurologists. This article reviews the current state of knowledge surrounding the prevalence, etiology, and neurobiology of conversion disorder. There have been improvements ...

journal_title：Neuropsychiatric disease and treatment

authors： Allin M,Streeruwitz A,Curtis V

更新日期：2005-09-01 00:00:00

abstract：:Peripheral benzodiazepine (BDZ) receptors were investigated by means of the binding of the specific ligand (3)H-PK 11195 to platelet membranes in patients suffering from bipolar disorder and in healthy controls. The results showed that the density (Bmax) of peripheral BDZ receptors was significantly higher in patients...

journal_title：Neuropsychiatric disease and treatment

authors： Marazziti D,Dell'Osso B,Baroni S,Masala I,Nasso ED,Giannaccini G,Dell'Osso L

更新日期：2005-06-01 00:00:00